DYNLT1 and ACOX2

Data Source:
BioGRID (two hybrid)

		DYNLT1	ACOX2
Description		dynein light chain Tctex-type 1	acyl-CoA oxidase 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Peroxisome Peroxisomal Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding	Acyl-CoA Oxidase Activity Fatty Acid Binding Protein Binding Palmitoyl-CoA Oxidase Activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase Activity Protein Homodimerization Activity Flavin Adenine Dinucleotide Binding FAD Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Very Long-chain Fatty Acid Metabolic Process Protein Targeting To Peroxisome Bile Acid Biosynthetic Process Positive Regulation Of Cell Death Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Lipid Homeostasis Positive Regulation Of Response To Oxidative Stress
Pathways		Neutrophil degranulation	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Beta-oxidation of pristanoyl-CoA Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS			Night sleep phenotypes ( 27126917) Systemic lupus erythematosus ( 28714469)
Interacting Genes		50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	3 interacting genes: CLK1 DYNLT1 PEX5
Entrez ID		6993	8309
HPRD ID		15987	09037
Ensembl ID		ENSG00000146425	ENSG00000168306
Uniprot IDs		P63172	Q99424
PDB IDs		5JPW
Enriched GO Terms of Interacting Partners?
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