UXT and RCAN1

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		UXT	RCAN1
Description		ubiquitously expressed prefoldin like chaperone	regulator of calcineurin 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Spindle Pole Gamma-tubulin Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton	Nucleus Cytoplasm
	Molecular Function	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Nucleic Acid Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Negative Regulation Of G0 To G1 Transition	Calcium-mediated Signaling Calcineurin-NFAT Signaling Cascade Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Transcriptional Regulation by E2F6
Drugs			Dipyridamole
Diseases
GWAS			Cancer ( 29299148) Rheumatoid arthritis ( 30423114 23143596 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		29 interacting genes: APP AR CECR2 DYNLT1 FBXO7 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	8 interacting genes: APP BTRC GSK3B MAP3K3 MAPK3 PPP3CA USP22 UXT
Entrez ID		8409	1827
HPRD ID		02209	04226
Ensembl ID		ENSG00000126756	ENSG00000159200
Uniprot IDs		Q9UBK9	B7Z1F0 E9PDJ2 P53805 Q6FGP2 Q6ZMM3 V9GYW9
PDB IDs			6UUQ
Enriched GO Terms of Interacting Partners?
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