DYNLT1 and ARID4B

Data Source:
BioGRID (two hybrid)

		DYNLT1	ARID4B
Description		dynein light chain Tctex-type 1	AT-rich interaction domain 4B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Cellular_component Nucleus Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding Molecular_function Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways		Neutrophil degranulation	HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS			Asthma ( 29273806) Monocyte percentage of white cells ( 32888494) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494)
Interacting Genes		50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	15 interacting genes: DNAAF6 DYNLT1 EAF1 ETS1 HNRNPA2B1 NHSL2 NTAQ1 PIK3R3 PLEKHF2 PRR23B PTGES3L-AARSD1 RANBP2 SAP130 SIN3A SPANXB1
Entrez ID		6993	51742
HPRD ID		15987	10661
Ensembl ID		ENSG00000146425	ENSG00000054267
Uniprot IDs		P63172	Q4LE39
PDB IDs		5JPW
Enriched GO Terms of Interacting Partners?
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