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RAD17 and HUS1
Data Source:
HPRD
(in vivo)
RAD17
HUS1
Description
RAD17 checkpoint clamp loader component
HUS1 checkpoint clamp component
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Nucleolus
Rad17 RFC-like Complex
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Checkpoint Clamp Complex
Site Of Double-strand Break
Molecular Function
Chromatin Binding
DNA Clamp Loader Activity
Protein Binding
ATP Binding
Protein Binding
Biological Process
DNA Replication Checkpoint
DNA Damage Checkpoint
DNA Replication
DNA Repair
Cellular Response To DNA Damage Stimulus
Negative Regulation Of DNA Replication
Intra-S DNA Damage Checkpoint
Mitotic DNA Replication Checkpoint
Regulation Of Phosphorylation
Regulation Of Signal Transduction By P53 Class Mediator
DNA Damage Checkpoint
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
Regulation Of Protein Phosphorylation
DNA Replication
DNA Repair
Nucleotide-excision Repair
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Response To UV
Embryo Development Ending In Birth Or Egg Hatching
Intra-S DNA Damage Checkpoint
Mitotic DNA Replication Checkpoint
Meiotic DNA Integrity Checkpoint
Cellular Response To Ionizing Radiation
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Blood urea nitrogen levels (
31152163
)
Gut microbiota alpha diversity (Shannon index) (
33208821
)
Obstructive sleep apnea during REM sleep (apnea hypopnea index) (
29077507
)
Interacting Genes
15 interacting genes:
ATM
ATR
HUS1
MCM7
POLE
PRKDC
PRMT6
RAD1
RAD9A
RAD9B
RFC2
RFC3
RFC4
SNU13
USP20
28 interacting genes:
C4orf46
CD200
DCUN1D5
DNAJC7
FEN1
GRIP1
HDAC1
HUS1B
MSH2
MSH3
MSH6
NEIL1
NTAQ1
OGG1
PCNA
POLB
RAD1
RAD17
RAD9A
RAD9B
RHNO1
RPA1
RPA2
SDCBP
SIRT6
TDG
TOPBP1
YWHAQ
Entrez ID
5884
3364
HPRD ID
09124
04787
Ensembl ID
ENSG00000152942
ENSG00000136273
Uniprot IDs
O75943
A4D2F2
O60921
PDB IDs
3A1J
3G65
3GGR
6J8Y
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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