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RAD17 and RFC3
Data Source:
BioGRID
(affinity chromatography technology, pull down)
RAD17
RFC3
Description
RAD17 checkpoint clamp loader component
replication factor C subunit 3
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Nucleolus
Rad17 RFC-like Complex
Nucleus
Nucleoplasm
DNA Replication Factor C Complex
Ctf18 RFC-like Complex
Molecular Function
Chromatin Binding
DNA Clamp Loader Activity
Protein Binding
ATP Binding
DNA Binding
DNA Clamp Loader Activity
Protein Binding
ATPase Activity
Single-stranded DNA Helicase Activity
Biological Process
DNA Replication Checkpoint
DNA Damage Checkpoint
DNA Replication
DNA Repair
Cellular Response To DNA Damage Stimulus
Negative Regulation Of DNA Replication
Intra-S DNA Damage Checkpoint
Mitotic DNA Replication Checkpoint
Regulation Of Phosphorylation
Regulation Of Signal Transduction By P53 Class Mediator
DNA Synthesis Involved In DNA Repair
DNA Replication
DNA-dependent DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Nucleotide-excision Repair, DNA Gap Filling
Translesion Synthesis
Telomere Maintenance Via Semi-conservative Replication
DNA Duplex Unwinding
Nucleotide-excision Repair, DNA Incision
Error-prone Translesion Synthesis
DNA Damage Response, Detection Of DNA Damage
Response To Organophosphorus
Error-free Translesion Synthesis
Positive Regulation Of DNA-directed DNA Polymerase Activity
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
Activation of ATR in response to replication stress
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Regulation of TP53 Activity through Phosphorylation
Polymerase switching
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Blood urea nitrogen levels (
31152163
)
Alzheimer's disease (
20061627
)
Colorectal cancer or advanced adenoma (
30510241
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Obesity-related traits (
23251661
)
Interacting Genes
15 interacting genes:
ATM
ATR
HUS1
MCM7
POLE
PRKDC
PRMT6
RAD1
RAD9A
RAD9B
RFC2
RFC3
RFC4
SNU13
USP20
13 interacting genes:
ANKRD40
ARFGAP1
CHTF8
INCA1
KHDRBS2
KHDRBS3
MESD
PCNA
PICK1
PTEN
RAD17
RFC1
RFC4
Entrez ID
5884
5983
HPRD ID
09124
02676
Ensembl ID
ENSG00000152942
ENSG00000133119
Uniprot IDs
O75943
A0A024RDQ8
P40938
PDB IDs
6VVO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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