RAD17 and RAD9B

Data Source:
HPRD (in vitro, in vivo)

		RAD17	RAD9B
Description		RAD17 checkpoint clamp loader component	RAD9 checkpoint clamp component B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Rad17 RFC-like Complex	Nucleus Nucleoplasm Checkpoint Clamp Complex
	Molecular Function	Chromatin Binding DNA Clamp Loader Activity Protein Binding ATP Binding	Protein Binding 3'-5' Exonuclease Activity
	Biological Process	DNA Replication Checkpoint DNA Damage Checkpoint DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Negative Regulation Of DNA Replication Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Regulation Of Phosphorylation Regulation Of Signal Transduction By P53 Class Mediator	DNA Replication Checkpoint DNA Replication DNA Repair Intra-S DNA Damage Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint	Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163)
Interacting Genes		15 interacting genes: ATM ATR HUS1 MCM7 POLE PRKDC PRMT6 RAD1 RAD9A RAD9B RFC2 RFC3 RFC4 SNU13 USP20	5 interacting genes: HUS1 HUS1B RAD1 RAD17 RAD9A
Entrez ID		5884	144715
HPRD ID		09124	12221
Ensembl ID		ENSG00000152942	ENSG00000151164
Uniprot IDs		O75943	A0A024RBJ5 A0A024RBN9 B4DX60 B4DYM6 J3KPN7 Q6WBX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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