HUS1 and RHNO1

Data Source:
BioGRID (pull down)

		HUS1	RHNO1
Description		HUS1 checkpoint clamp component	RAD9-HUS1-RAD1 interacting nuclear orphan 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Checkpoint Clamp Complex Site Of Double-strand Break	Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Damage Checkpoint Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Regulation Of Protein Phosphorylation DNA Replication DNA Repair Nucleotide-excision Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Response To UV Embryo Development Ending In Birth Or Egg Hatching Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Meiotic DNA Integrity Checkpoint Cellular Response To Ionizing Radiation Regulation Of Signal Transduction By P53 Class Mediator	DNA Damage Checkpoint Recombinational Repair DNA Replication Cell Cycle Cellular Response To UV Positive Regulation Of G0 To G1 Transition Cellular Response To Ionizing Radiation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint	HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Gut microbiota alpha diversity (Shannon index) ( 33208821) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		28 interacting genes: C4orf46 CD200 DCUN1D5 DNAJC7 FEN1 GRIP1 HDAC1 HUS1B MSH2 MSH3 MSH6 NEIL1 NTAQ1 OGG1 PCNA POLB RAD1 RAD17 RAD9A RAD9B RHNO1 RPA1 RPA2 SDCBP SIRT6 TDG TOPBP1 YWHAQ	12 interacting genes: BANP CYSRT1 GOLGA2 HUS1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LZTS2 RAD1 RAD9A TFIP11 TOPBP1
Entrez ID		3364	83695
HPRD ID		04787	17487
Ensembl ID		ENSG00000136273	ENSG00000171792
Uniprot IDs		A4D2F2 O60921	Q9BSD3
PDB IDs		3A1J 3G65 3GGR 6J8Y	6J8Y
Enriched GO Terms of Interacting Partners?
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