Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CDK5RAP2 and CLIP4
Data Source:
BioGRID
(two hybrid)
CDK5RAP2
CLIP4
Description
CDK5 regulatory subunit associated protein 2
CAP-Gly domain containing linker protein family member 4
Image
No pdb structure
GO Annotations
Cellular Component
Pericentriolar Material
Spindle Pole
Cytoplasm
Golgi Apparatus
Centrosome
Cytosol
Cytoskeleton
Microtubule
Gamma-tubulin Ring Complex
Cell Junction
Microtubule Plus-end
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Mitotic Spindle Pole
Nucleus
Cytoplasm
Microtubule Plus-end
Intracellular Membrane-bounded Organelle
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Protein Binding
Calmodulin Binding
Microtubule Binding
Tubulin Binding
Protein Kinase Binding
Gamma-tubulin Binding
Protein Binding
Microtubule Plus-end Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Establishment Of Mitotic Spindle Orientation
Microtubule Cytoskeleton Organization
Microtubule Bundle Formation
Chromosome Segregation
Centrosome Cycle
Centriole Replication
Brain Development
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Neurogenesis
Microtubule Organizing Center Organization
Positive Regulation Of Microtubule Polymerization
Regulation Of Neuron Differentiation
Negative Regulation Of Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Centriole Replication
Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Ciliary Basal Body-plasma Membrane Docking
Cytoplasmic Microtubule Organization
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
Primary microcephaly (MCPH)
GWAS
Asthma (
27611488
)
Height (
28552196
)
Photic sneeze reflex (
27182965
)
Response to statin therapy (
20339536
)
Rheumatoid arthritis (
24782177
)
Metabolite levels (
23823483
)
Interacting Genes
25 interacting genes:
ABCA2
CDK5
CDK5R1
CLIP4
CRMP1
EEF1G
ERG28
FBXO25
HAP1
KAT5
LUC7L2
MAGEH1
MAPRE1
NEFL
PCBD1
PTN
RBM48
REPS2
SENP2
STARD9
STK36
TBC1D4
TRIM37
TSNAX
ZPR1
33 interacting genes:
APP
CDK5RAP2
CLIP1
CMYA5
DCAF6
DES
DST
GLP1R
HSF2BP
JAKMIP2
KIF1B
KIFC3
LZTS2
MAGEA12
MAP7
MAP7D1
MEOX2
MYBPC1
MYH3
PDE4DIP
PEG10
SIX2
SON
TACC3
TAF1
TNNT1
TNNT3
TPM1
TRIM32
TRIP13
TTN
TULP3
ZNF114
Entrez ID
55755
79745
HPRD ID
09740
08634
Ensembl ID
ENSG00000136861
ENSG00000115295
Uniprot IDs
A0A0A0MRG9
B3KVI2
B9EG74
Q7Z3M0
Q96SN8
A8K6D0
B7Z936
Q8N3C7
PDB IDs
2Z0W
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?