CDK5RAP2 and STK36

Data Source:
HPRD (two hybrid)

		CDK5RAP2	STK36
Description		CDK5 regulatory subunit associated protein 2	serine/threonine kinase 36
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Spindle Pole Cytoplasm Golgi Apparatus Centrosome Cytosol Cytoskeleton Microtubule Gamma-tubulin Ring Complex Cell Junction Microtubule Plus-end Perinuclear Region Of Cytoplasm Extracellular Exosome Mitotic Spindle Pole	Extracellular Region Nucleus Cytoplasm Cytosol
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Calmodulin Binding Microtubule Binding Tubulin Binding Protein Kinase Binding Gamma-tubulin Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Chromosome Segregation Centrosome Cycle Centriole Replication Brain Development Regulation Of G2/M Transition Of Mitotic Cell Cycle Neurogenesis Microtubule Organizing Center Organization Positive Regulation Of Microtubule Polymerization Regulation Of Neuron Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Centriole Replication Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Ciliary Basal Body-plasma Membrane Docking	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Protein Phosphorylation Smoothened Signaling Pathway Positive Regulation Of Hh Target Transcription Factor Activity Brain Development Post-embryonic Development Positive Regulation Of Smoothened Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Cilium Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs			Fostamatinib
Diseases		Primary microcephaly (MCPH)
GWAS		Asthma ( 27611488) Height ( 28552196) Photic sneeze reflex ( 27182965) Response to statin therapy ( 20339536) Rheumatoid arthritis ( 24782177)	Amyotrophic lateral sclerosis ( 22959728) Hematocrit ( 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Male-pattern baldness ( 28196072) Red blood cell count ( 32888494) Refractive error ( 32231278)
Interacting Genes		25 interacting genes: ABCA2 CDK5 CDK5R1 CLIP4 CRMP1 EEF1G ERG28 FBXO25 HAP1 KAT5 LUC7L2 MAGEH1 MAPRE1 NEFL PCBD1 PTN RBM48 REPS2 SENP2 STARD9 STK36 TBC1D4 TRIM37 TSNAX ZPR1	10 interacting genes: CDK5RAP2 CDK9 CLNK FRMPD4 GLI1 GLI2 GLI3 MAST2 MID1 SUFU
Entrez ID		55755	27148
HPRD ID		09740	09631
Ensembl ID		ENSG00000136861	ENSG00000163482
Uniprot IDs		A0A0A0MRG9 B3KVI2 B9EG74 Q7Z3M0 Q96SN8	A0A140VJW1 Q9NRP7
PDB IDs
Enriched GO Terms of Interacting Partners?
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