PPP3R2 and MLH3

Data Source:
BioGRID (two hybrid)

		PPP3R2	MLH3
Description		protein phosphatase 3 regulatory subunit B, beta	mutL homolog 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Synaptonemal Complex Male Germ Cell Nucleus Nucleus Nucleoplasm Chiasma Mismatch Repair Complex
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity	Chromatin Binding Satellite DNA Binding Protein Binding ATP Binding ATPase Activity Centromeric DNA Binding Mismatched DNA Binding
	Biological Process	Regulation Of Phosphoprotein Phosphatase Activity	Mismatch Repair Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Female Meiosis I Protein Localization
Pathways			Meiotic recombination
Drugs		Cyclosporine Voclosporin
Diseases			Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS			Inflammatory bowel disease ( 23128233) Mood instability ( 29187730) Refractive error ( 32231278)
Interacting Genes		19 interacting genes: APC AURKA BUB1 CCND1 CD14 DLC1 DYNLL1 FBXW7 KRT34 MLH3 MSH2 PDGFRL PPP3CA PTPN12 PTPRJ RAB32 SMAD4 TBC1D10C TFCP2	45 interacting genes: AKT1 ALDOB ANP32B AOPEP AR BAAT CCDC180 CDC14B CDK8 CTSV CYLC2 DVL1 FANCC FBP1 FBP2 FRAT2 GALNT12 HEMGN HRAS HSD17B3 IGFBP3 LEF1 MAP2K1 MLH1 MSANTD3 MSH4 NANS PPP2CB PPP3R2 RASA1 SEC61B SFRP2 SMAD1 STX17 TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRIM55 TRIM63 TSTD2 XPA ZDHHC17 ZNF510
Entrez ID		5535	27030
HPRD ID		10164	05094
Ensembl ID		ENSG00000188386	ENSG00000119684
Uniprot IDs		Q96LZ3	Q2M1Z1 Q9UHC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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