MLH3 and TBC1D2

Data Source:
BioGRID (two hybrid)

		MLH3	TBC1D2
Description		mutL homolog 3	TBC1 domain family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Male Germ Cell Nucleus Nucleus Nucleoplasm Chiasma Mismatch Repair Complex	Nucleoplasm Cytosol Plasma Membrane Cell Junction Cytoplasmic Vesicle
	Molecular Function	Chromatin Binding Satellite DNA Binding Protein Binding ATP Binding ATPase Activity Centromeric DNA Binding Mismatched DNA Binding	GTPase Activator Activity Protein Binding Cadherin Binding
	Biological Process	Mismatch Repair Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Female Meiosis I Protein Localization	Intracellular Protein Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Meiotic recombination	TBC/RABGAPs
Drugs
Diseases		Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS		Inflammatory bowel disease ( 23128233) Mood instability ( 29187730) Refractive error ( 32231278)	Metabolite levels ( 23823483) Post-traumatic stress disorder ( 26114229) Rate of ventricular enlargement ( 31711042) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		45 interacting genes: AKT1 ALDOB ANP32B AOPEP AR BAAT CCDC180 CDC14B CDK8 CTSV CYLC2 DVL1 FANCC FBP1 FBP2 FRAT2 GALNT12 HEMGN HRAS HSD17B3 IGFBP3 LEF1 MAP2K1 MLH1 MSANTD3 MSH4 NANS PPP2CB PPP3R2 RASA1 SEC61B SFRP2 SMAD1 STX17 TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRIM55 TRIM63 TSTD2 XPA ZDHHC17 ZNF510	9 interacting genes: AURKA BUB1 CCND1 DCC GABARAPL1 KCTD6 MAP1LC3A MLH3 PDGFRL
Entrez ID		27030	55357
HPRD ID		05094	11624
Ensembl ID		ENSG00000119684	ENSG00000095383
Uniprot IDs		Q2M1Z1 Q9UHC1	A0A024R166 Q9BYX2
PDB IDs			2DHK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?