ATP5F1C and PJA1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5F1C	PJA1
Description		ATP synthase F1 subunit gamma	praja ring finger ubiquitin ligase 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Sector F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane	Cytoplasm
	Molecular Function	RNA Binding Protein Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Oxidative Phosphorylation ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport	Protein Ubiquitination Protein Catabolic Process
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases
GWAS			Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		29 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CDC42 CHMP2B DPP3 DUX4 EGFR ELOF1 ERCC6 FBXO7 GDPD2 ITIH2 MED15 MEOX2 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337	64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440
Entrez ID		509	64219
HPRD ID		00156	02335
Ensembl ID		ENSG00000165629	ENSG00000181191
Uniprot IDs		B4DL14 P36542 Q8TAS0	Q8NG27
PDB IDs			2L0B
Enriched GO Terms of Interacting Partners?
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