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NME4 and TTC19
Data Source:
BioGRID
(two hybrid)
NME4
TTC19
Description
NME/NM23 nucleoside diphosphate kinase 4
tetratricopeptide repeat domain 19
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Mitochondrial Matrix
Mitochondrion
Mitochondrial Inner Membrane
Centrosome
Midbody
Respirasome
Molecular Function
Nucleoside Diphosphate Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Cardiolipin Binding
Protein Binding
Biological Process
Nucleoside Diphosphate Phosphorylation
GTP Biosynthetic Process
UTP Biosynthetic Process
CTP Biosynthetic Process
Lipid Transport
Nucleoside Metabolic Process
Nucleobase-containing Small Molecule Interconversion
Mitotic Cytokinesis
Mitochondrial Respiratory Chain Complex III Assembly
Pathways
Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Body mass index (
26426971
)
Red blood cell traits (
23446634
)
Interacting Genes
40 interacting genes:
ABI2
ARMC7
ATPAF2
C14orf119
C1orf109
CABP2
CABP5
CCDC102B
CCDC57
CDKN2D
CFAP206
CIB1
CIB3
CIDEB
CLNK
DTX2
HDAC7
HSF2BP
LMO4
LSM8
MKRN3
MLH1
NME1
NME1-NME2
NME7
NUTF2
NXF1
POLR1C
PSMB1
SOCS3
SPG21
SUV39H2
TNS4
TRAPPC2
TRAPPC2B
TRIP13
TSSK3
TTC19
UBL5
ZBTB16
44 interacting genes:
AGXT
APRT
ATXN1
C20orf85
CCDC33
CHMP4A
COA6
CYSLTR2
DMRT3
EIF4ENIF1
FAM136A
FAM217B
FH
FTO
GORASP2
GPANK1
HOXD12
HPS6
IHO1
L3MBTL3
LDB2
MLN
MXRA8
NAB2
NME4
POU6F2
PRR35
RBP1
REL
RUSC1
RXFP3
SH2D4A
SHISA6
SLC22A18AS
SMG9
SPRED1
TBX2
TCAP
UBA1
UPF3B
USP20
USP54
WASHC1
ZNF688
Entrez ID
4833
54902
HPRD ID
03489
07899
Ensembl ID
ENSG00000103202
ENSG00000011295
Uniprot IDs
A0A087WVT9
O00746
A0A024RD83
Q6DKK2
PDB IDs
1EHW
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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