TTC19 and FAM136A

Data Source:
BioGRID (two hybrid)

		TTC19	FAM136A
Description		tetratricopeptide repeat domain 19	family with sequence similarity 136 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Acne (severe) ( 24927181) LDL cholesterol ( 30275531) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Response to citalopram or escitalopram in depression ( 27622933) Total cholesterol levels ( 30275531)
Interacting Genes		44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688	11 interacting genes: ANKRD11 DPY30 MAGEB4 MBD3 MEIS2 NTAQ1 P4HA3 PSMB1 RUNX1T1 SMARCD1 TTC19
Entrez ID		54902	84908
HPRD ID		07899	07866
Ensembl ID		ENSG00000011295	ENSG00000035141
Uniprot IDs		A0A024RD83 Q6DKK2	B0AZT6 E7EQY1 Q96C01
PDB IDs
Enriched GO Terms of Interacting Partners?
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