TTC19 and COA6

Data Source:
BioGRID (two hybrid)

		TTC19	COA6
Description		tetratricopeptide repeat domain 19	cytochrome c oxidase assembly factor 6
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome	Nucleoplasm Mitochondrion Mitochondrial Intermembrane Space Plasma Membrane Respiratory Chain Complex IV
	Molecular Function	Protein Binding	RNA Binding Copper Ion Binding Protein Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly	Respiratory Chain Complex IV Assembly Plasma Membrane ATP Synthesis Coupled Electron Transport
Pathways			Mitochondrial protein import
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688	3 interacting genes: CABP2 DTX2 TTC19
Entrez ID		54902	388753
HPRD ID		07899	18535
Ensembl ID		ENSG00000011295	ENSG00000168275
Uniprot IDs		A0A024RD83 Q6DKK2	Q5JTJ3
PDB IDs			6NL3 6PCE 6PCF
Enriched GO Terms of Interacting Partners?
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