TTC19 and APRT

Data Source:
BioGRID (two hybrid)

		TTC19	APRT
Description		tetratricopeptide repeat domain 19	adenine phosphoribosyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome	Extracellular Region Nucleoplasm Cytoplasm Cytosol Secretory Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Adenine Binding Adenine Phosphoribosyltransferase Activity Protein Binding AMP Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly	Purine Ribonucleoside Salvage Adenine Salvage Lactation Grooming Behavior Cellular Response To Insulin Stimulus Purine-containing Compound Salvage Neutrophil Degranulation AMP Salvage
Pathways			Neutrophil degranulation Purine salvage
Drugs			Adenine 5-O-phosphono-alpha-D-ribofuranosyl diphosphate 9-Deazaadenine Citric acid
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome	Adenine phosphoribosyltransferase deficiency; 2,8-Dihydroxyadenine urolithiasis
GWAS			Hair color ( 26926045)
Interacting Genes		44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688	5 interacting genes: APP IKBKG MLH1 SUMO2 TTC19
Entrez ID		54902	353
HPRD ID		07899	00029
Ensembl ID		ENSG00000011295	ENSG00000198931
Uniprot IDs		A0A024RD83 Q6DKK2	P07741
PDB IDs			1OPU 1ORE 1ZN7 1ZN8 1ZN9 4X44 4X45 6FCH 6FCI 6FCL 6FD4 6FD5 6FD6 6HGP 6HGQ 6HGR 6HGS
Enriched GO Terms of Interacting Partners?
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