NME4 and TNS4

Data Source:
BioGRID (two hybrid)

		NME4	TNS4
Description		NME/NM23 nucleoside diphosphate kinase 4	tensin 4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix	Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding Cardiolipin Binding	Actin Binding Protein Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Lipid Transport Nucleoside Metabolic Process Nucleobase-containing Small Molecule Interconversion	Apoptotic Process Protein Localization
Pathways		Interconversion of nucleotide di- and triphosphates	MET interacts with TNS proteins
Drugs
Diseases
GWAS		Body mass index ( 26426971) Red blood cell traits ( 23446634)	Asthma ( 31959851) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042)
Interacting Genes		40 interacting genes: ABI2 ARMC7 ATPAF2 C14orf119 C1orf109 CABP2 CABP5 CCDC102B CCDC57 CDKN2D CFAP206 CIB1 CIB3 CIDEB CLNK DTX2 HDAC7 HSF2BP LMO4 LSM8 MKRN3 MLH1 NME1 NME1-NME2 NME7 NUTF2 NXF1 POLR1C PSMB1 SOCS3 SPG21 SUV39H2 TNS4 TRAPPC2 TRAPPC2B TRIP13 TSSK3 TTC19 UBL5 ZBTB16	25 interacting genes: AR CARD9 CBL CYSRT1 EGFR ERBB3 ERBB4 GAB1 GSTCD HSF2BP KAZN KCTD4 MET NME4 NR3C1 P4HA2 PIH1D1 PIK3R1 PPP3CA RABEP1 RPAIN TRIM21 TRIM27 TXK ZRANB1
Entrez ID		4833	84951
HPRD ID		03489	12223
Ensembl ID		ENSG00000103202	ENSG00000131746
Uniprot IDs		A0A087WVT9 O00746	Q6PJP3 Q8IZW8
PDB IDs		1EHW
Enriched GO Terms of Interacting Partners?
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