PSMC3IP and RB1CC1

Data Source:
BioGRID (two hybrid)

		PSMC3IP	RB1CC1
Description		PSMC3 interacting protein	RB1 inducible coiled-coil 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	DNA Binding Nuclear Receptor Coactivator Activity	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Reciprocal Meiotic Recombination Positive Regulation Of Transcription, DNA-templated	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Meiotic recombination	Macroautophagy
Drugs
Diseases
GWAS		Colorectal or endometrial cancer ( 26621817) White blood cell count ( 32888494)	Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		20 interacting genes: AR AURKA BCAR3 BRMS1 CASP8 CHEK2 ERBB2 ESR1 ESR2 FGFR4 FZR1 NOTCH2 NR3C1 PIK3CA PSMC3 RB1CC1 RXRA TGFB1 THRB XRCC3	33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1
Entrez ID		29893	9821
HPRD ID		16362	06019
Ensembl ID		ENSG00000131470	ENSG00000023287
Uniprot IDs		A0A158RUX1 K7ERB6 Q9P2W1	Q8TDY2
PDB IDs			6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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