SLCO3A1 and PDZD3

Data Source:
HPRD (two hybrid)

		SLCO3A1	PDZD3
Description		solute carrier organic anion transporter family member 3A1	PDZ domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell
	Molecular Function	Sodium-independent Organic Anion Transmembrane Transporter Activity	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Prostaglandin Transport Sodium-independent Organic Anion Transport Positive Regulation Of NF-kappaB Transcription Factor Activity Transmembrane Transport Transport Across Blood-brain Barrier	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane
Pathways			Intestinal infectious diseases
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Adult body size ( 32376654) Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Diastolic blood pressure ( 30224653) DNA methylation (variation) ( 23725790) Estimated glomerular filtration rate reduction (30%) ( 30955190) Gastroesophageal reflux disease ( 27485664) Inattentive symptoms ( 18821565) Neuritic plaque ( 25188341) Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio ( 26634245) Primary sclerosing cholangitis ( 27992413) Refractive error ( 32231278) Response to iloperidone treatment (QT prolongation) ( 18521091) Smoking initiation ( 24665060)
Interacting Genes		7 interacting genes: AQP6 C4orf3 GOLM1 PDZD3 SLC9A3R1 SLC9A3R2 TRARG1	18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8
Entrez ID		28232	79849
HPRD ID		07502	06191
Ensembl ID		ENSG00000176463	ENSG00000172367
Uniprot IDs		Q9UIG8	B0YJ61 Q86UT5
PDB IDs			2V90
Enriched GO Terms of Interacting Partners?
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