PDZD3 and SLCO1C1

Data Source:
HPRD (two hybrid)

		PDZD3	SLCO1C1
Description		PDZ domain containing 3	solute carrier organic anion transporter family member 1C1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	Bile Acid Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity
	Biological Process	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane	Bile Acid And Bile Salt Transport Sodium-independent Organic Anion Transport Transmembrane Transport Thyroid Hormone Transport Transport Across Blood-brain Barrier Positive Regulation Of Thyroid Hormone Generation
Pathways		Intestinal infectious diseases	Transport of organic anions
Drugs
Diseases
GWAS			Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Height ( 20881960 25282103 18391951) Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	1 interacting genes: PDZD3
Entrez ID		79849	53919
HPRD ID		06191	08342
Ensembl ID		ENSG00000172367	ENSG00000139155
Uniprot IDs		B0YJ61 Q86UT5	Q9NYB5
PDB IDs		2V90
Enriched GO Terms of Interacting Partners?
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