PDZD3 and CFTR

PDZD3

CFTR

Description PDZ domain containing 3 CF transmembrane conductance regulator
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Barrett's esophagus or Esophageal adenocarcinoma ( 27527254)
  • Glaucoma ( 30054594)
  • Gout ( 22179738)
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
  • Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8 29 interacting genes: CANX CLCN3 DERL1 DNAJA1 DNAJC5 EZR GOPC HSP90AA1 MARCHF2 NHS PDZD3 PDZK1 PPP2R1B PRKAA1 PRKACA PRKAR2A PRKCA PRKCE PRKG1 RNF5 SLC4A7 SLC4A8 SLC9A3R1 SLC9A3R2 SLC9A6 SNAP23 STUB1 STX1A UBE2I
Entrez ID 79849 1080
HPRD ID 06191 03883
Ensembl ID ENSG00000172367 ENSG00000001626
Uniprot IDs B0YJ61 Q86UT5 A0A024R730 P13569
PDB IDs 2V90 1NBD 1XMI 1XMJ 2BBO 2BBS 2BBT 2LOB 2PZE 2PZF 2PZG 3GD7 3ISW 4WZ6 5D2D 5D3E 5D3F 5TF7 5TF8 5TFA 5TFB 5TFC 5TFD 5TFF 5TFG 5TFI 5TFJ 5TGK 5UAK 6GJQ 6GJS 6GJU 6GK4 6GKD 6HEP 6MSM 6O1V 6O2P 6UK1
Enriched GO Terms of Interacting Partners?
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