PDZD3 and SLC15A2

Data Source:
HPRD (two hybrid)

		PDZD3	SLC15A2
Description		PDZ domain containing 3	solute carrier family 15 member 2
Image
GO Annotations	Cellular Component	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Spanning Component Of Plasma Membrane Extracellular Exosome Spanning Component Of Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity
	Biological Process	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane	Ion Transport Protein Transport Peptidoglycan Transport Xenobiotic Transport Dipeptide Transport Innate Immune Response Renal Absorption Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Dipeptide Import Across Plasma Membrane Transport Across Blood-brain Barrier Proton Transmembrane Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Intestinal infectious diseases	Proton/oligopeptide cotransporters
Drugs			Ampicillin Cefotaxime Oxacillin Benzylpenicillin
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	26 interacting genes: ADAM12 ANKS1A AQP1 C11orf87 CHRD ENKD1 KLHL38 KPRP KRT34 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP6-3 LMO4 NTAQ1 OTX1 PDZD3 PDZK1 PITX1 PLSCR4 SMARCC1 TENT5B TLX3 VENTX WWOX
Entrez ID		79849	6565
HPRD ID		06191	09088
Ensembl ID		ENSG00000172367	ENSG00000163406
Uniprot IDs		B0YJ61 Q86UT5	Q16348
PDB IDs		2V90	6EZI
Enriched GO Terms of Interacting Partners?
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