PDZD3 and SLCO1A2

Data Source:
HPRD (two hybrid)

		PDZD3	SLCO1A2
Description		PDZ domain containing 3	solute carrier organic anion transporter family member 1A2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	Organic Anion Transmembrane Transporter Activity Bile Acid Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity
	Biological Process	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane	Organic Anion Transport Bile Acid And Bile Salt Transport Sodium-independent Organic Anion Transport Transmembrane Transport
Pathways		Intestinal infectious diseases	Recycling of bile acids and salts Transport of organic anions
Drugs
Diseases
GWAS			AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875) Bilirubin levels ( 19414484) Diisocyanate-induced asthma ( 25918132) Methotrexate phramacokinetics (acute lymphoblastic leukemia) ( 19901119) Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Progressive supranuclear palsy ( 30089514 21685912) Serum metabolite levels ( 23093944) Statin-induced myopathy (severe) ( 31220337)
Interacting Genes		18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	4 interacting genes: PDZD3 PDZK1 SLC9A3R1 SLC9A3R2
Entrez ID		79849	6579
HPRD ID		06191	09112
Ensembl ID		ENSG00000172367	ENSG00000084453
Uniprot IDs		B0YJ61 Q86UT5	A0A024RAT5 P46721
PDB IDs		2V90
Enriched GO Terms of Interacting Partners?
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