BRMS1 and RBP1

Data Source:
HPRD (in vivo)

		BRMS1	RBP1
Description		BRMS1 transcriptional repressor and anoikis regulator	retinol binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleoplasm Lipid Droplet Cytosol
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Retinoid Binding Protein Binding Retinal Binding All-trans-retinol Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Retinoid Metabolic Process Retinoic Acid Biosynthetic Process Vitamin A Metabolic Process Lipid Homeostasis
Pathways		HDACs deacetylate histones Potential therapeutics for SARS	Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport
Drugs			Acitretin
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	18 interacting genes: BRMS1 BRMS1L CYTOR DHPS HDAC1 HDAC2 IKBKG ING1 LRAT LRP2 MED26 RBBP4 RBBP7 SAP30 SIN3A TNFRSF10D TTC19 UBE2J2
Entrez ID		25855	5947
HPRD ID		05879	07036
Ensembl ID		ENSG00000174744	ENSG00000114115
Uniprot IDs		G5E9I4 Q9HCU9	A0A0A0MQT0 P09455
PDB IDs		2XUS 4AUV	5H8T 5H9A 5HA1 5HBS 5LJB 5LJC 5LJD 5LJE 5LJG 5LJH 5LJK 6E5L 6E5T 6E6M
Enriched GO Terms of Interacting Partners?
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