BRMS1 and THRSP

Data Source:
BioGRID (two hybrid)

		BRMS1	THRSP
Description		BRMS1 transcriptional repressor and anoikis regulator	thyroid hormone responsive
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleoplasm Cytosol
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Lipid Metabolic Process Carnitine Shuttle Response To Bacterium Regulation Of Triglyceride Biosynthetic Process Regulation Of Lipid Biosynthetic Process
Pathways		HDACs deacetylate histones Potential therapeutics for SARS	Carnitine metabolism
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Menarche (age at onset) ( 25231870) Tourette syndrome ( 30818990)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	25 interacting genes: AKT1 AURKA BAG4 BCAR3 BRMS1 ERBB2 FGFR4 FZR1 HMMR IGF1R INCA1 KRAS LSP1 PALB2 PARP1 PIK3CA PTPN1 RB1CC1 SMAD4 STK11 TEPSIN TGFB1 TSG101 WT1 ZMYND12
Entrez ID		25855	7069
HPRD ID		05879	03566
Ensembl ID		ENSG00000174744	ENSG00000151365
Uniprot IDs		G5E9I4 Q9HCU9	Q92748
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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