OSTF1 and DTX3

Data Source:
BioGRID (two hybrid)

		OSTF1	DTX3
Description		osteoclast stimulating factor 1	deltex E3 ubiquitin ligase 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Intracellular Anatomical Structure Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding SH3 Domain Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ossification Signal Transduction Neutrophil Degranulation	Notch Signaling Pathway Protein Ubiquitination
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Allergic rhinitis ( 25085501) Glucose homeostasis traits ( 25524916) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Resting-state electroencephalogram vigilance ( 29703947) Systemic sclerosis ( 30247649) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		51 interacting genes: AGR2 APP BORCS6 CBL CBLB CCDC33 CRX CTDSP1 CUEDC1 DPPA4 DTX3 EFS ERRFI1 FASLG FBXO7 GAPDH GGN HES7 HTT KHDRBS1 KLHL42 LATS1 LMNA MAPK6 MED19 MEOX2 NFYC NUTM1 NUTM2F PBX4 PICK1 REL RP2 SDCBP SF1 SF3A2 SMN1 SNW1 SOCS7 SYNGAP1 TRIB3 TRIM54 VPS37B WASF1 WASHC1 WASL YPEL3 ZBTB42 ZBTB7B ZNF655 ZNF688	44 interacting genes: ARF5 BAG3 DTX1 DTX2 EPM2AIP1 FAM90A1 FYN GRB2 MAPK9 NCK2 NFKBID NOTCH2 OSTF1 PARP11 PTK6 RNF141 RNF38 TCEANC TRAF4 TRIP10 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP YES1 ZDHHC17 ZMYND19
Entrez ID		26578	196403
HPRD ID		17808	16842
Ensembl ID		ENSG00000134996	ENSG00000178498
Uniprot IDs		Q92882	A0A024RB96 Q8N9I9
PDB IDs		1X2K 1ZLM 3EHQ 3EHR
Enriched GO Terms of Interacting Partners?
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