DTX3 and OSTF1

Data Source:
BioGRID (two hybrid)

		DTX3	OSTF1
Description		deltex E3 ubiquitin ligase 3	osteoclast stimulating factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Extracellular Region Intracellular Anatomical Structure Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding SH3 Domain Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Ossification Signal Transduction Neutrophil Degranulation
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Allergic rhinitis ( 25085501) Glucose homeostasis traits ( 25524916) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Resting-state electroencephalogram vigilance ( 29703947) Systemic sclerosis ( 30247649) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		44 interacting genes: ARF5 BAG3 DTX1 DTX2 EPM2AIP1 FAM90A1 FYN GRB2 MAPK9 NCK2 NFKBID NOTCH2 OSTF1 PARP11 PTK6 RNF141 RNF38 TCEANC TRAF4 TRIP10 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP YES1 ZDHHC17 ZMYND19	51 interacting genes: AGR2 APP BORCS6 CBL CBLB CCDC33 CRX CTDSP1 CUEDC1 DPPA4 DTX3 EFS ERRFI1 FASLG FBXO7 GAPDH GGN HES7 HTT KHDRBS1 KLHL42 LATS1 LMNA MAPK6 MED19 MEOX2 NFYC NUTM1 NUTM2F PBX4 PICK1 REL RP2 SDCBP SF1 SF3A2 SMN1 SNW1 SOCS7 SYNGAP1 TRIB3 TRIM54 VPS37B WASF1 WASHC1 WASL YPEL3 ZBTB42 ZBTB7B ZNF655 ZNF688
Entrez ID		196403	26578
HPRD ID		16842	17808
Ensembl ID		ENSG00000178498	ENSG00000134996
Uniprot IDs		A0A024RB96 Q8N9I9	Q92882
PDB IDs			1X2K 1ZLM 3EHQ 3EHR
Enriched GO Terms of Interacting Partners?
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