OSTF1 and RP2

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		OSTF1	RP2
Description		osteoclast stimulating factor 1	RP2 activator of ARL3 GTPase
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GO Annotations	Cellular Component	Extracellular Region Intracellular Anatomical Structure Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Nucleoplasm Cytoplasm Golgi Apparatus Centriole Plasma Membrane Cilium Nuclear Body Cytoplasmic Vesicle Ciliary Basal Body Extracellular Exosome Periciliary Membrane Compartment
	Molecular Function	Protein Binding SH3 Domain Binding	Magnesium Ion Binding GTPase Activator Activity Protein Binding GTP Binding Unfolded Protein Binding
	Biological Process	Ossification Signal Transduction Neutrophil Degranulation	Cell Morphogenesis Protein Folding Post-Golgi Vesicle-mediated Transport Post-chaperonin Tubulin Folding Pathway Visual Perception Protein Transport Positive Regulation Of GTPase Activity
Pathways		Neutrophil degranulation	Trafficking of myristoylated proteins to the cilium
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Allergic rhinitis ( 25085501) Glucose homeostasis traits ( 25524916) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Resting-state electroencephalogram vigilance ( 29703947) Systemic sclerosis ( 30247649) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		51 interacting genes: AGR2 APP BORCS6 CBL CBLB CCDC33 CRX CTDSP1 CUEDC1 DPPA4 DTX3 EFS ERRFI1 FASLG FBXO7 GAPDH GGN HES7 HTT KHDRBS1 KLHL42 LATS1 LMNA MAPK6 MED19 MEOX2 NFYC NUTM1 NUTM2F PBX4 PICK1 REL RP2 SDCBP SF1 SF3A2 SMN1 SNW1 SOCS7 SYNGAP1 TRIB3 TRIM54 VPS37B WASF1 WASHC1 WASL YPEL3 ZBTB42 ZBTB7B ZNF655 ZNF688	3 interacting genes: ARL3 OSTF1 PM20D2
Entrez ID		26578	6102
HPRD ID		17808	02424
Ensembl ID		ENSG00000134996	ENSG00000102218
Uniprot IDs		Q92882	A0A1B2JLU2 O75695
PDB IDs		1X2K 1ZLM 3EHQ 3EHR	2BX6 3BH6 3BH7
Enriched GO Terms of Interacting Partners?
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