OSTF1 and GAPDH

Data Source:
BioGRID (two hybrid)

		OSTF1	GAPDH
Description		osteoclast stimulating factor 1	glyceraldehyde-3-phosphate dehydrogenase
Image
GO Annotations	Cellular Component	Extracellular Region Intracellular Anatomical Structure Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Lipid Droplet Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome GAIT Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding SH3 Domain Binding	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Aspartic-type Endopeptidase Inhibitor Activity Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding Disordered Domain Specific Binding
	Biological Process	Ossification Signal Transduction Neutrophil Degranulation	Microtubule Cytoskeleton Organization Positive Regulation Of Cytokine Production Gluconeogenesis Glycolytic Process Negative Regulation Of Endopeptidase Activity Regulation Of Macroautophagy Negative Regulation Of Translation Killing Of Cells Of Other Organism Peptidyl-cysteine S-trans-nitrosylation Protein Stabilization Defense Response To Fungus Neuron Apoptotic Process Killing By Host Of Symbiont Cells Canonical Glycolysis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Interferon-gamma
Pathways		Neutrophil degranulation	Glycolysis Gluconeogenesis
Drugs			NADH Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Xanthinol Copper Artenimol
Diseases
GWAS		Allergic rhinitis ( 25085501) Glucose homeostasis traits ( 25524916) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Resting-state electroencephalogram vigilance ( 29703947) Systemic sclerosis ( 30247649) Urinary magnesium-to-creatinine ratio ( 29093028)	Blood protein levels ( 30072576)
Interacting Genes		51 interacting genes: AGR2 APP BORCS6 CBL CBLB CCDC33 CRX CTDSP1 CUEDC1 DPPA4 DTX3 EFS ERRFI1 FASLG FBXO7 GAPDH GGN HES7 HTT KHDRBS1 KLHL42 LATS1 LMNA MAPK6 MED19 MEOX2 NFYC NUTM1 NUTM2F PBX4 PICK1 REL RP2 SDCBP SF1 SF3A2 SMN1 SNW1 SOCS7 SYNGAP1 TRIB3 TRIM54 VPS37B WASF1 WASHC1 WASL YPEL3 ZBTB42 ZBTB7B ZNF655 ZNF688	84 interacting genes: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DUX4 DYNLL1 EGFR ERBB2 FBXO7 FKBP6 GADD45A GAS7 GOT2 GRIA2 GRM1 HES1 HNF4G HSPB2 HTT ITGB5 KARS1 KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 LINC01554 MAPK1 MTNR1A MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 PTPRF RAB2A RBM5 RPA2 RXFP4 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ
Entrez ID		26578	2597
HPRD ID		17808	00713
Ensembl ID		ENSG00000134996	ENSG00000111640
Uniprot IDs		Q92882	P04406 V9HVZ4
PDB IDs		1X2K 1ZLM 3EHQ 3EHR	1U8F 1ZNQ 2FEH 3GPD 4WNC 4WNI 6ADE 6IQ6 6YND 6YNE 6YNF 6YNH
Enriched GO Terms of Interacting Partners?
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