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OSTF1 and LATS1
Data Source:
BioGRID
(two hybrid)
OSTF1
LATS1
Description
osteoclast stimulating factor 1
large tumor suppressor kinase 1
Image
GO Annotations
Cellular Component
Extracellular Region
Intracellular Anatomical Structure
Secretory Granule Lumen
Ficolin-1-rich Granule Lumen
Spindle Pole
Nucleus
Microtubule Organizing Center
Cytosol
Midbody
Molecular Function
Protein Binding
SH3 Domain Binding
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Estrogen Receptor Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Ossification
Signal Transduction
Neutrophil Degranulation
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Sister Chromatid Segregation
Inner Cell Mass Cell Fate Commitment
Inner Cell Mass Cellular Morphogenesis
Protein Phosphorylation
Hormone-mediated Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Peptidyl-serine Phosphorylation
Keratinocyte Differentiation
Regulation Of Actin Filament Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Cellular Protein Localization
Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Organ Growth
Cytoplasmic Sequestering Of Protein
Cell Division
Mammary Gland Epithelial Cell Differentiation
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways
Neutrophil degranulation
Signaling by Hippo
Drugs
Fostamatinib
Diseases
GWAS
Allergic rhinitis (
25085501
)
Glucose homeostasis traits (
25524916
)
Loneliness (
29970889
)
Loneliness (MTAG) (
29970889
)
Resting-state electroencephalogram vigilance (
29703947
)
Systemic sclerosis (
30247649
)
Urinary magnesium-to-creatinine ratio (
29093028
)
Brain morphology (MOSTest) (
32665545
)
Nicotine dependence and major depression (severity of comorbidity) (
30287806
)
Subcortical volume (MOSTest) (
32665545
)
Testicular germ cell tumor (
28604728
)
Interacting Genes
51 interacting genes:
AGR2
APP
BORCS6
CBL
CBLB
CCDC33
CRX
CTDSP1
CUEDC1
DPPA4
DTX3
EFS
ERRFI1
FASLG
FBXO7
GAPDH
GGN
HES7
HTT
KHDRBS1
KLHL42
LATS1
LMNA
MAPK6
MED19
MEOX2
NFYC
NUTM1
NUTM2F
PBX4
PICK1
REL
RP2
SDCBP
SF1
SF3A2
SMN1
SNW1
SOCS7
SYNGAP1
TRIB3
TRIM54
VPS37B
WASF1
WASHC1
WASL
YPEL3
ZBTB42
ZBTB7B
ZNF655
ZNF688
48 interacting genes:
ALPP
APP
ARPC3
AURKB
CAV1
CBY2
CDC26
CDK1
CEP76
EIF4EBP1
FOXL2
FSD2
GOLGA2
KRT31
LDOC1
LIMK1
LRRK2
MAGI3
MOAP1
MOB3A
MOB3B
MOB3C
MOB4
NEDD4
NF2
NUAK1
NUAK2
OSTF1
PABPN1
PPM1F
PPP1R11
PPP6R3
PTEN
RAC1
SMURF1
SMURF2
SSX2IP
STK3
STK4
TAZ
TFIP11
TRAF1
UBE2I
UBQLN2
WWOX
WWP1
WWTR1
ZYX
Entrez ID
26578
9113
HPRD ID
17808
09147
Ensembl ID
ENSG00000134996
ENSG00000131023
Uniprot IDs
Q92882
O95835
PDB IDs
1X2K
1ZLM
3EHQ
3EHR
4ZRK
5B5W
5BRK
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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