DTX3 and PARP11

Data Source:
BioGRID (two hybrid)

		DTX3	PARP11
Description		deltex E3 ubiquitin ligase 3	poly(ADP-ribose) polymerase family member 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	NAD+ ADP-ribosyltransferase Activity Protein ADP-ribosylase Activity
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Nuclear Envelope Organization Spermatogenesis Protein Transport Cell Differentiation MRNA Transport Protein Auto-ADP-ribosylation Protein Mono-ADP-ribosylation
Pathways
Drugs
Diseases
GWAS			Cognitive performance ( 20125193) Colorectal cancer ( 23263487) Emotional lability in attention deficit hyperactivity disorder ( 31085060) Fasting insulin (dietary factor interaction) ( 24204828) Hematocrit ( 29403010) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494) Pulse pressure ( 27841878) Red blood cell count ( 29403010) Total hippocampal volume ( 30279459) White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)
Interacting Genes		44 interacting genes: ARF5 BAG3 DTX1 DTX2 EPM2AIP1 FAM90A1 FYN GRB2 MAPK9 NCK2 NFKBID NOTCH2 OSTF1 PARP11 PTK6 RNF141 RNF38 TCEANC TRAF4 TRIP10 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP YES1 ZDHHC17 ZMYND19	7 interacting genes: DTX3 GTPBP3 HOOK2 LHX3 LHX4 MDFI TRIP13
Entrez ID		196403	57097
HPRD ID		16842	15101
Ensembl ID		ENSG00000178498	ENSG00000111224
Uniprot IDs		A0A024RB96 Q8N9I9	Q9NR21
PDB IDs			2DK6
Enriched GO Terms of Interacting Partners?
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