GPSM1 and USP9X

Data Source:
BioGRID (pull down)

		GPSM1	USP9X
Description		G protein signaling modulator 1	ubiquitin specific peptidase 9 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex	Nucleus Cytoplasm Cytosol Membrane Growth Cone
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Co-SMAD Binding Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Protein Targeting To Peroxisome Cell Cycle Chromosome Segregation Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Cell Migration Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation BMP Signaling Pathway Regulation Of Circadian Rhythm Cellular Protein Metabolic Process Rhythmic Process Axon Extension Protein Stabilization Cell Division Protein K48-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Demethylation
Pathways		G alpha (i) signalling events	Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Peroxisomal protein import Peroxisomal protein import Amyloid fiber formation
Drugs
Diseases
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 32499647 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)	Migraine ( 27322543)
Interacting Genes		26 interacting genes: BHLHE40 CCDC158 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1	25 interacting genes: AFDN ALDH1A3 BCL9 CTNNB1 DCX DVL2 ERG FBXW7 GPSM1 MAP3K5 MCL1 NEAT1 PEX5 PSD4 PTEN RNF115 SMAD2 SMAD4 SMN2 SMURF1 STIL SUMO2 TDRD3 UBC VHL
Entrez ID		26086	8239
HPRD ID		17075	02091
Ensembl ID		ENSG00000160360	ENSG00000124486
Uniprot IDs		A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5	Q6P468 Q86X58 Q93008
PDB IDs			5VBD 5WCH
Enriched GO Terms of Interacting Partners?
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