GPSM1 and FAM83A

Data Source:
BioGRID (two hybrid)

		GPSM1	FAM83A
Description		G protein signaling modulator 1	family with sequence similarity 83 member A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex	Cytoplasm
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding	Protein Binding Protein Kinase Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Population Proliferation
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 32499647 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)	Urinary uromodulin levels ( 24578125)
Interacting Genes		26 interacting genes: BHLHE40 CCDC158 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1	23 interacting genes: BHLHE40 CYSRT1 DAZAP2 FOXH1 FOXI1 GCC1 GPSM1 KRT34 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MGAT5B NCK2 PLAGL2 PPP1R16B PRDM14 PSMA3 QARS1 SMYD1 TRIM23 TRIM27 UBASH3A
Entrez ID		26086	84985
HPRD ID		17075	17489
Ensembl ID		ENSG00000160360	ENSG00000147689
Uniprot IDs		A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5	Q86UY5
PDB IDs			4URJ
Enriched GO Terms of Interacting Partners?
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