USP9X and NEAT1

Data Source:
BioGRID (unspecified method)

		USP9X	NEAT1
Description		ubiquitin specific peptidase 9 X-linked	nuclear paraspeckle assembly transcript 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Growth Cone	Paraspeckles
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Co-SMAD Binding Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	Protein Binding MiRNA Binding RISC Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Protein Targeting To Peroxisome Cell Cycle Chromosome Segregation Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Cell Migration Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation BMP Signaling Pathway Regulation Of Circadian Rhythm Cellular Protein Metabolic Process Rhythmic Process Axon Extension Protein Stabilization Cell Division Protein K48-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Demethylation	Gene Silencing By MiRNA Positive Regulation Of Inflammatory Response Negative Regulation Of Gene Silencing By MiRNA Positive Regulation Of Synoviocyte Proliferation
Pathways		Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Peroxisomal protein import Peroxisomal protein import Amyloid fiber formation
Drugs
Diseases
GWAS		Migraine ( 27322543)	Acne (severe) ( 24927181) Glaucoma (primary open-angle) ( 29891935)
Interacting Genes		25 interacting genes: AFDN ALDH1A3 BCL9 CTNNB1 DCX DVL2 ERG FBXW7 GPSM1 MAP3K5 MCL1 NEAT1 PEX5 PSD4 PTEN RNF115 SMAD2 SMAD4 SMN2 SMURF1 STIL SUMO2 TDRD3 UBC VHL	11 interacting genes: CTSD GAR1 HACD3 MPC2 NEDD4L PINK1 RIMBP2 TRAF6 TUBB4A TUBB4B USP9X
Entrez ID		8239	283131
HPRD ID		02091
Ensembl ID		ENSG00000124486	ENSG00000245532
Uniprot IDs		Q6P468 Q86X58 Q93008
PDB IDs		5VBD 5WCH
Enriched GO Terms of Interacting Partners?
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