GPSM1 and ZBED1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GPSM1	ZBED1
Description		G protein signaling modulator 1	zinc finger BED-type containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex	Chromatin Nucleus Nucleoplasm Centrosome PML Body Nuclear Membrane
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity SUMO Ligase Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Viral Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Protein Autosumoylation
Pathways		G alpha (i) signalling events	SUMOylation of chromatin organization proteins
Drugs
Diseases
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 32499647 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)
Interacting Genes		26 interacting genes: BHLHE40 CCDC158 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1	55 interacting genes: AMOTL2 ATRX C1orf109 CCDC13 CDC37 CTNNAL1 DGCR6 EFHC1 FABP4 FAM124B FANCG FNDC11 GGACT GORASP2 GPN1 GPSM1 KDM1A KIFC3 KLHL40 LCN2 LNX1 LRRC20 MAD2L2 MAGEB2 MKKS MLH1 MPST MYO15B NCDN NIF3L1 NIP7 NTAQ1 NUDT18 PAX6 PIAS2 PICK1 POLE2 POLR1C PRKAA1 PRKAR1A PSAP RENBP RIN1 SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2 TRAPPC2B TRIML2 TTC23 TTR UBE2I UCHL5 USP2
Entrez ID		26086	9189
HPRD ID		17075	02170
Ensembl ID		ENSG00000160360	ENSG00000214717
Uniprot IDs		A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5	A0A024RBU4 O96006
PDB IDs			2CT5
Enriched GO Terms of Interacting Partners?
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