GPSM1 and DCAF11

Data Source:
BioGRID (two hybrid)

		GPSM1	DCAF11
Description		G protein signaling modulator 1	DDB1 and CUL4 associated factor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Protein-containing Complex	Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding	Protein Binding
	Biological Process	Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		G alpha (i) signalling events	Neddylation
Drugs
Diseases
GWAS		Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Offspring birth weight ( 31043758) Type 2 diabetes ( 30297969 29632382 26818947 23945395 31118516 32499647 30718926 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)
Interacting Genes		26 interacting genes: BHLHE40 CCDC158 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1	13 interacting genes: AGR2 CDKN1A DDB1 GPSM1 NFE2L2 PTEN RCN1 SLBP TNNI1 TNNI2 TNS2 TRIM55 TRIM63
Entrez ID		26086	80344
HPRD ID		17075	18297
Ensembl ID		ENSG00000160360	ENSG00000100897
Uniprot IDs		A0A087WVF5 A0A0A0MRC4 A0A0A0MSK4 Q86YR5	B3KSW2 Q59GN6 Q8TEB1
PDB IDs
Enriched GO Terms of Interacting Partners?
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