ELAVL1 and ANP32A

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		ELAVL1	ANP32A
Description		ELAV like RNA binding protein 1	acidic nuclear phosphoprotein 32 family member A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Cytoplasmic Stress Granule Membrane Postsynapse Glutamatergic Synapse Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Protein Kinase Binding MiRNA Binding MRNA 3'-UTR AU-rich Region Binding Protein Homodimerization Activity	RNA Binding Protein Binding Histone Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Import Into Nucleus Posttranscriptional Gene Silencing Regulation Of MRNA Stability Positive Regulation Of Translation MRNA Stabilization Protein Homooligomerization Negative Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Population Maintenance	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability
Pathways		HuR (ELAVL1) binds and stabilizes mRNA mRNA Splicing - Major Pathway	HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	Esophageal cancer ( 21642993)
Interacting Genes		37 interacting genes: ANP32A ANP32B APOE C12orf75 CARM1 CELF2 CHEK2 CTNNB1 ERG FAF2 GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VCP VEGFA XIAP	29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		1994	8125
HPRD ID		16025	09014
Ensembl ID		ENSG00000066044	ENSG00000140350
Uniprot IDs		Q15717	A0A384P5U2 P39687
PDB IDs		3HI9 4ED5 4EGL 4FXV 5SZW 6G2K 6GC5 6GD1 6GD2 6GD3	2JE0 2JE1 4XOS
Enriched GO Terms of Interacting Partners?
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