ANP32A and E4F1

Data Source:
HPRD (two hybrid, in vivo)

		ANP32A	E4F1
Description		acidic nuclear phosphoprotein 32 family member A	E4F transcription factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Spindle
	Molecular Function	RNA Binding Protein Binding Histone Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transferase Activity CAMP Response Element Binding Metal Ion Binding
	Biological Process	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Cell Cycle Process Viral Process Protein Ubiquitination Regulation Of Growth Positive Regulation Of Transcription By RNA Polymerase II Cell Division Mitotic Cell Cycle Arrest
Pathways		HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Esophageal cancer ( 21642993)
Interacting Genes		29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1	14 interacting genes: ANP32A ATM ATR CDKN2A EHMT2 HMGA2 KRTAP10-4 KRTAP10-7 PRKDC RASSF1 RB1 SMAD9 TP53 UPF2
Entrez ID		8125	1877
HPRD ID		09014	04317
Ensembl ID		ENSG00000140350	ENSG00000167967
Uniprot IDs		A0A384P5U2 P39687	Q66K89
PDB IDs		2JE0 2JE1 4XOS
Enriched GO Terms of Interacting Partners?
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