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ELAVL1 and FAF2
Data Source:
BioGRID
(pull down)
ELAVL1
FAF2
Description
ELAV like RNA binding protein 1
Fas associated factor family member 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Cytosol
Cytoplasmic Stress Granule
Membrane
Postsynapse
Glutamatergic Synapse
Ribonucleoprotein Complex
Extracellular Region
Endoplasmic Reticulum
Lipid Droplet
VCP-NPL4-UFD1 AAA ATPase Complex
Azurophil Granule Lumen
Molecular Function
RNA Binding
Double-stranded RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Protein Kinase Binding
MiRNA Binding
MRNA 3'-UTR AU-rich Region Binding
Protein Homodimerization Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Lipase Binding
Ubiquitin Binding
Lipase Inhibitor Activity
Biological Process
MRNA Splicing, Via Spliceosome
Protein Import Into Nucleus
Posttranscriptional Gene Silencing
Regulation Of MRNA Stability
Positive Regulation Of Translation
MRNA Stabilization
Protein Homooligomerization
Negative Regulation Of Gene Silencing By MiRNA
3'-UTR-mediated MRNA Stabilization
Regulation Of Stem Cell Population Maintenance
Response To Unfolded Protein
Ubiquitin-dependent ERAD Pathway
Retrograde Protein Transport, ER To Cytosol
Lipid Droplet Organization
Negative Regulation Of Catalytic Activity
Neutrophil Degranulation
Pathways
HuR (ELAVL1) binds and stabilizes mRNA
mRNA Splicing - Major Pathway
Neutrophil degranulation
Drugs
Diseases
GWAS
Blood protein levels (
28240269
)
Interacting Genes
37 interacting genes:
ANP32A
ANP32B
APOE
C12orf75
CARM1
CELF2
CHEK2
CTNNB1
ERG
FAF2
GJB3
HNRNPK
HOTAIR
IL7R
KPNA1
KPNB1
MIRLET7B
MIRLET7I
NOS3
PAIP2
PLAU
PLAUR
PRKCA
PRKCD
PRKCE
PSEN2
PTBP2
PTGS2
RBFOX2
SDCBP
SET
SREK1
TNPO1
TNPO2
VCP
VEGFA
XIAP
11 interacting genes:
ELAVL1
FAF1
FAS
MAP3K1
PCAT1
PNPLA2
PSMD2
SMURF1
UBE2D1
UBE3A
VCP
Entrez ID
1994
23197
HPRD ID
16025
16870
Ensembl ID
ENSG00000066044
ENSG00000113194
Uniprot IDs
Q15717
Q96CS3
PDB IDs
3HI9
4ED5
4EGL
4FXV
5SZW
6G2K
6GC5
6GD1
6GD2
6GD3
2DAM
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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