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ELAVL1 and MIRLET7B
Data Source:
BioGRID
(unspecified method, affinity chromatography technology)
ELAVL1
MIRLET7B
Description
ELAV like RNA binding protein 1
microRNA let-7b
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Cytosol
Cytoplasmic Stress Granule
Membrane
Postsynapse
Glutamatergic Synapse
Ribonucleoprotein Complex
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Molecular Function
RNA Binding
Double-stranded RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Protein Kinase Binding
MiRNA Binding
MRNA 3'-UTR AU-rich Region Binding
Protein Homodimerization Activity
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
Protein Import Into Nucleus
Posttranscriptional Gene Silencing
Regulation Of MRNA Stability
Positive Regulation Of Translation
MRNA Stabilization
Protein Homooligomerization
Negative Regulation Of Gene Silencing By MiRNA
3'-UTR-mediated MRNA Stabilization
Regulation Of Stem Cell Population Maintenance
Negative Regulation Of Autophagy
Cellular Response To Reactive Oxygen Species
Gene Silencing By MiRNA
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways
HuR (ELAVL1) binds and stabilizes mRNA
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Blood protein levels (
28240269
)
Interacting Genes
37 interacting genes:
ANP32A
ANP32B
APOE
C12orf75
CARM1
CELF2
CHEK2
CTNNB1
ERG
FAF2
GJB3
HNRNPK
HOTAIR
IL7R
KPNA1
KPNB1
MIRLET7B
MIRLET7I
NOS3
PAIP2
PLAU
PLAUR
PRKCA
PRKCD
PRKCE
PSEN2
PTBP2
PTGS2
RBFOX2
SDCBP
SET
SREK1
TNPO1
TNPO2
VCP
VEGFA
XIAP
99 interacting genes:
ADARB1
AGO2
AIMP1
AIMP2
APOBEC3B
ATXN2L
C1QBP
CELF1
CPSF1
CPSF6
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX23
DDX3X
DDX3Y
DHX36
DHX37
EIF2AK2
ELAVL1
EPRS1
ERAL1
ESRP1
FAM98A
FIP1L1
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
P3H1
PDCD11
PGAM5
PLOD1
PTBP1
PUF60
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM4B
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
SYMPK
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
TUT7
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
1994
406884
HPRD ID
16025
Ensembl ID
ENSG00000066044
ENSG00000284520
Uniprot IDs
Q15717
PDB IDs
3HI9
4ED5
4EGL
4FXV
5SZW
6G2K
6GC5
6GD1
6GD2
6GD3
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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