ANP32A and KPNA6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ANP32A	KPNA6
Description		acidic nuclear phosphoprotein 32 family member A	karyopherin subunit alpha 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Membrane Host Cell
	Molecular Function	RNA Binding Protein Binding Histone Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability	NLS-bearing Protein Import Into Nucleus Viral Genome Replication Mitigation Of Host Defenses By Symbiont Positive Regulation Of Transcription By RNA Polymerase II Maternal Process Involved In Female Pregnancy Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Viral Life Cycle
Pathways		HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Esophageal cancer ( 21642993)	Body mass index ( 26426971)
Interacting Genes		29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1	37 interacting genes: ANKRD11 ANP32A ANP32B ARNT BRCA1 CDKN1B CREBBP CSE1L DCPS EPAS1 FAM90A1 FRG1BP GEMIN2 HIF1A IL1A JRK KAT5 KEAP1 KPNB1 LMNA LMNB1 MAGED1 NMNAT1 NOP2 NUP50 POLR3C POM121 POU6F2 RAC1 RELB RNMT SKP2 SMARCB1 STAT1 STAT3 TAF9 ZNF131
Entrez ID		8125	23633
HPRD ID		09014	09465
Ensembl ID		ENSG00000140350	ENSG00000025800
Uniprot IDs		A0A384P5U2 P39687	O60684
PDB IDs		2JE0 2JE1 4XOS	4UAD
Enriched GO Terms of Interacting Partners?
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