IL24 and RB1CC1

Data Source:
BioGRID (two hybrid)

		IL24	RB1CC1
Description		interleukin 24	RB1 inducible coiled-coil 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Apoptotic Process Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Migration Wound Healing Serine Phosphorylation Of STAT Protein Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-4	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Macroautophagy Regulation Of Macroautophagy Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Interleukin-20 family signaling	Macroautophagy
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		25 interacting genes: AKT1 APC ATM BAG4 CASP8 CCR5 CLU DCD ESR2 FBXW7 HMMR HRAS IL20RA KRAS LSP1 NOTCH2 PALB2 PARP1 PIK3CA PTEN RAD51 RARG RB1CC1 RIPK3 SMAD4	33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1
Entrez ID		11009	9821
HPRD ID		04995	06019
Ensembl ID		ENSG00000162892	ENSG00000023287
Uniprot IDs		Q13007	Q8TDY2
PDB IDs		6DF3 6GG1	6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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