PDLIM7 and SH3BP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PDLIM7	SH3BP2
Description		PDZ and LIM domain 7	SH3 domain binding protein 2
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GO Annotations	Cellular Component	Stress Fiber Ruffle Nucleoplasm Cytosol Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding	Phosphotyrosine Residue Binding SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding
	Biological Process	Ossification Receptor-mediated Endocytosis Axon Guidance Heart Development Actin Cytoskeleton Organization Positive Regulation Of Osteoblast Differentiation Muscle Structure Development	Signal Transduction Positive Regulation Of Signal Transduction
Pathways		RET signaling
Drugs
Diseases			Cherubism
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Huntington's disease progression ( 28642124) Multiple sclerosis ( 24076602)
Interacting Genes		34 interacting genes: AP5B1 BSG CCDC185 DGCR6 ENKD1 FNDC11 GEM GFAP HNRNPD IQGAP1 MDM2 PAK5 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165	24 interacting genes: ABL1 ARHGAP10 DBNL ERBB2 FGFR1 FLT3 FYN GRB2 LAT LCK NSD2 PDLIM7 PLCG1 PLCG2 SH3KBP1 STAT3 SYK TF TNKS2 VAV1 VAV2 VAV3 YWHAQ ZAP70
Entrez ID		9260	6452
HPRD ID		10436	03657
Ensembl ID		ENSG00000196923	ENSG00000087266
Uniprot IDs		Q9NR12	A0A384N6E5 P78314
PDB IDs		2Q3G	2CR4 3TWR
Enriched GO Terms of Interacting Partners?
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