PDLIM7 and PHF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PDLIM7	PHF1
Description		PDZ and LIM domain 7	PHD finger protein 1
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GO Annotations	Cellular Component	Stress Fiber Ruffle Nucleoplasm Cytosol Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin	Nucleus Nucleoplasm Cytoplasm Centrosome ESC/E(Z) Complex Site Of Double-strand Break
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding	DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Ossification Receptor-mediated Endocytosis Axon Guidance Heart Development Actin Cytoskeleton Organization Positive Regulation Of Osteoblast Differentiation Muscle Structure Development	Chromatin Organization Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation
Pathways		RET signaling	PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
Interacting Genes		34 interacting genes: AP5B1 BSG CCDC185 DGCR6 ENKD1 FNDC11 GEM GFAP HNRNPD IQGAP1 MDM2 PAK5 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165	24 interacting genes: ATXN7L1 BIRC7 BRD2 CALCOCO2 EZH2 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C6 H3C7 H3C8 H4C1 HSD17B14 NAB2 NEK6 PDLIM7 RBPMS TFCP2 THAP1 TRIM23 VAC14
Entrez ID		9260	5252
HPRD ID		10436	04195
Ensembl ID		ENSG00000196923	ENSG00000112511
Uniprot IDs		Q9NR12	A0A140VJR4 A0A1U9X8A3 O43189
PDB IDs		2Q3G	2E5P 2M0O 4HCZ 5XFN 5XFO 5XFP
Enriched GO Terms of Interacting Partners?
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