SH3BP2 and PLCG2

  • Number of citations of the paper that reports this interaction (PubMedID 11390470)
  • 26
  • Data Source:
  • HPRD (in vivo)

SH3BP2

PLCG2

Description SH3 domain binding protein 2 phospholipase C gamma 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 28714976)
  • Blood protein levels ( 30072576)
  • Breast cancer (menopausal hormone therapy interaction) ( 24080446)
  • Coronary artery disease ( 29212778)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Height ( 28552196)
  • Inflammatory bowel disease ( 28067908)
  • Mean platelet volume ( 27863252)
  • Metabolite levels ( 23823483)
  • Platelet distribution width ( 27863252)
  • Ulcerative colitis ( 28067908)
  • Upper eyelid morphology ( 29921221)
  • Venous thromboembolism ( 31420334 31676865)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 24 interacting genes: ABL1 ARHGAP10 DBNL ERBB2 FGFR1 FLT3 FYN GRB2 LAT LCK NSD2 PDLIM7 PLCG1 PLCG2 SH3KBP1 STAT3 SYK TF TNKS2 VAV1 VAV2 VAV3 YWHAQ ZAP70 50 interacting genes: ASB9 BLK BLNK BTK CBLB CD19 DAPP1 EGFR ELK1 EPOR EPYC ESD FCER1G FLT1 FYN GAB1 GAB2 GABPB2 HCK HSPD1 IRS1 ISL1 ITK JAK1 JAK2 KCTD17 KDR KHDRBS1 LAT LAT2 LCK LCP2 LHX8 LIME1 LYN NPM1 PRKD1 PTPN6 PTTG1 RALBP1 RTL10 SETD9 SH3BP2 SHC1 SYK TEC TP53 TWIST2 ZKSCAN7 ZNF512B
Entrez ID 6452 5336
HPRD ID 03657 02570
Ensembl ID ENSG00000087266 ENSG00000197943
Uniprot IDs A0A384N6E5 P78314 P16885
PDB IDs 2CR4 3TWR 2K2J 2W2W 2W2X
Enriched GO Terms of Interacting Partners?
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