PHF1 and NAB2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PHF1	NAB2
Description		PHD finger protein 1	NGFI-A binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome ESC/E(Z) Complex Site Of Double-strand Break	Nucleus
	Molecular Function	DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Methylated Histone Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation	Endochondral Ossification Regulation Of Transcription, DNA-templated Schwann Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase III Myelination Regulation Of Epidermis Development Positive Regulation Of Tau-protein Kinase Activity
Pathways		PRC2 methylates histones and DNA	NGF-stimulated transcription NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31361310 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) IgE levels ( 22075330) Schizophrenia ( 25056061 29483656)
Interacting Genes		24 interacting genes: ATXN7L1 BIRC7 BRD2 CALCOCO2 EZH2 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C6 H3C7 H3C8 H4C1 HSD17B14 NAB2 NEK6 PDLIM7 RBPMS TFCP2 THAP1 TRIM23 VAC14	34 interacting genes: CCDC33 CCHCR1 CWF19L2 DGCR6 EGR1 EGR2 GCC1 JAKMIP2 KRT40 KRTAP10-3 KRTAP10-8 LENG1 LMNA MAPK3 MCM7 MDFI MORF4L1 NEDD9 NME7 NOTCH2NLA PHF1 PHOSPHO2 PIN1 RBPMS RFC5 SCNM1 SUMO1P1 TCEANC TCHP TGIF2LY TLE5 TTC19 ZBED8 ZMYND19
Entrez ID		5252	4665
HPRD ID		04195	03854
Ensembl ID		ENSG00000112511	ENSG00000166886
Uniprot IDs		A0A140VJR4 A0A1U9X8A3 O43189	Q15742
PDB IDs		2E5P 2M0O 4HCZ 5XFN 5XFO 5XFP
Enriched GO Terms of Interacting Partners?
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