PHF1 and ATXN7L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PHF1	ATXN7L1
Description		PHD finger protein 1	ataxin 7 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome ESC/E(Z) Complex Site Of Double-strand Break
	Molecular Function	DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Methylated Histone Binding Metal Ion Binding	Protein Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation
Pathways		PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)	Alzheimer's disease (late onset) ( 22881374) Blond vs. brown/black hair color ( 30531825) Dental caries ( 23064961) Heel bone mineral density ( 30598549 28869591) Obesity-related traits ( 23251661) Smoking cessation in chronic obstructive pulmonary disease ( 29631575)
Interacting Genes		24 interacting genes: ATXN7L1 BIRC7 BRD2 CALCOCO2 EZH2 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C6 H3C7 H3C8 H4C1 HSD17B14 NAB2 NEK6 PDLIM7 RBPMS TFCP2 THAP1 TRIM23 VAC14	5 interacting genes: KRT31 KRTAP10-9 PHF1 SP4 SSPOP
Entrez ID		5252	222255
HPRD ID		04195	12508
Ensembl ID		ENSG00000112511	ENSG00000146776
Uniprot IDs		A0A140VJR4 A0A1U9X8A3 O43189	A4D0Q3 Q9BTQ8 Q9ULK2
PDB IDs		2E5P 2M0O 4HCZ 5XFN 5XFO 5XFP
Enriched GO Terms of Interacting Partners?
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