TCAP and MYOZ1

Number of citations of the paper that reports this interaction (PubMedID 10984498)
36

Data Source:
HPRD (in vitro)

		TCAP	MYOZ1
Description		titin-cap	myozenin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Z Disc I Band	Nucleus Actin Cytoskeleton Z Disc Pseudopodium
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein Binding, Bridging Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding	Actin Binding Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Telethonin Binding FATZ Binding
	Biological Process	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Protein-containing Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Myofibril Assembly Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Skeletal Muscle Tissue Regeneration Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Striated Muscle Contraction
Drugs
Diseases		Limb-girdle muscular dystrophy (LGMD)
GWAS		Alcohol consumption ( 31358974) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Ulcerative colitis ( 20228799)	Atrial fibrillation ( 30061737)
Interacting Genes		17 interacting genes: ANKRD2 ATXN1 CRK FAS FYN HSPB2 LHX4 MDM2 MSTN MYOZ1 MYOZ3 PDPK1 RELA SIVA1 TRIM55 TRIM63 TTN	14 interacting genes: ACTN1 ACTN2 ACTN4 APP BRCA1 FLNC GRB2 LDB3 MAGEA11 PNKP PRKAA2 TCAP TRIM55 TRIM63
Entrez ID		8557	58529
HPRD ID		05133	05725
Ensembl ID		ENSG00000173991	ENSG00000177791
Uniprot IDs		A2TDC0 O15273	Q9NP98
PDB IDs		1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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