FLNB and PSEN1

  • Number of citations of the paper that reports this interaction (PubMedID 9437013)
  • 21
  • Data Source:
  • BioGRID (two hybrid, pull down)
  • HPRD (two hybrid, in vitro, in vivo)

FLNB

PSEN1

Description filamin B presenilin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065)
  • Eating disorders (purging via substances) ( 23568457)
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Height ( 31217584)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Immature fraction of reticulocytes ( 27863252)
  • Optic cup area ( 25631615 31798171 28073927)
  • Pulse pressure ( 30578418)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
  • Systemic sclerosis ( 31672989)
  • Vertical cup-disc ratio ( 28073927)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 20 interacting genes: ASB2 ATF7IP FBLIM1 FLNA GP1BA HSPB1 ITGB1 ITGB3 ITGB6 MLH1 NPHP1 PLEKHO1 PSEN1 PSEN2 PTEN RAD21 SMURF2 TRIM55 TSC22D2 TSHR 91 interacting genes: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DLL1 DOCK3 ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 MAPK9 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RHEB RMDN3 RNF32 RYR2 SCAF11 SCN1A ST13 STAMBPL1 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1
Entrez ID 2317 5663
HPRD ID 04543 00087
Ensembl ID ENSG00000136068 ENSG00000080815
Uniprot IDs O75369 A0A024R6A3 A0A0S2Z4D2 P49768
PDB IDs 2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L 5DCP 2KR6 4UIS 5A63 5FN2 5FN3 5FN4 5FN5 6IDF 6IYC
Enriched GO Terms of Interacting Partners?
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