PRKDC and POU2F1

  • Number of citations of the paper that reports this interaction (PubMedID 14612514)
  • 21
  • Data Source:
  • BioGRID (enzymatic study)

PRKDC

POU2F1

Description protein kinase, DNA-activated, catalytic subunit POU class 2 homeobox 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 31619474)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
  • Diastolic blood pressure ( 30224653)
  • Liver enzyme levels ( 18940312)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes 89 interacting genes: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CCNB1 CHEK1 CHEK2 CHUK CIB1 CLK1 CTDP1 DCAF1 DCLRE1C E4F1 EIF2S2 EIF4EBP1 EP300 ERG FH GSK3A GSK3B GZMB H1-1 H1-2 H2AX HDAC3 HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11 MTNR1B NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R3 PRKCD RAD17 RASSF1 RBBP8 RPA1 RPA2 SGO1 SP1 SRF SUMO2 THRA THRB TOP1 TP53 TREX1 UBE2I USF1 WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ ZBTB7A 49 interacting genes: APP AR BARD1 BRCA1 CEBPE CREB1 ESR1 FDXR HCFC1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 PRKACA PRKDC RARA RELA RXRA SNAPC4 SOX2 SP1 SP4 STAT5A STAT5B TBP THRA TLE4 TLE5 TLX2 TNF TXNRD1 VDR XRCC6
Entrez ID 5591 5451
HPRD ID 02941 01250
Ensembl ID ENSG00000253729 ENSG00000143190
Uniprot IDs P78527 A0A024R8Y2 P14859
PDB IDs 5LUQ 5W1R 5Y3R 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU
Enriched GO Terms of Interacting Partners?
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